ASH 2022 | Dec 10-13, 2022 | New Orleans, LA

PhasED-Seq® data presented at the 64th American Society of Hematology Annual Meeting & Exposition

American Society of Hematology

Foresight Diagnostics' PhasED-Seq ctDNA detection enables accurate treatment response monitoring and clinical prognosis in patients with B-cell lymphomas.

Mark Roschewski Headshot

Oral Presentation

Saturday, Dec 10, 2022 @4:45 PM CT | session 627, Theater AB

MRD-Negativity as a Potential Surrogate Endpoint after Frontline DLBCL Therapy: Pooled Analysis of Trials & Implications for Clinical Trial Design

Mark Roschewski, MD, of the National Cancer Institute will present data showing that PhasED-Seq's sensitivity exceeded that of PET/CT scans and was highly prognostic for outcomes when used to measure MRD at the end of treatment in 5 clinical trials of patients with DLBCL.

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David Kurtz Headshot

poster presentation

Saturday, Dec 10, 2022 @5:30 - 7:30 PM CT | session 621, Hall D

Ultrasensitive MRD Profiling Predicts Outcomes in DLBCL after Frontline Therapy with Tafasitamab in Combination with Lenalidomide and R-CHOP

David M. Kurtz, MD PhD, of the Stanford University School of Medicine has authored a poster presenting data on the use of PhasED-Seq to accurately track therapeutic response and predict clinical outcomes of first line therapy combinations in de novo DLBCL.

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David Kurtz Headshot

Oral Presentation

monday, Dec 12, 2022 @5:45 PM CT | session 704, Hall E

Ultrasensitive Circulating Tumor DNA (ctDNA) Dynamics after Autologous CD30.CAR-T Cell Therapy for Relapsed or Refractory (r/r) Classical Hodgkin Lymphoma (CHARIOT Study)

Dr. Kurtz gives an oral presentation of data from the CHARIOT phase 2 clinical trial that supports PhasED-Seq ctDNA detection as a viable biomarker to assess risk, monitor response, and predict outcomes in patients with recurrent classic Hodgkin Lymphoma treated with CD30.CAR-T therapy.

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“We are very pleased to have been selected by ASH to share these impactful clinical studies utilizing Foresight's PhasED-Seq MRD technology for guiding lymphoma treatments and furthering clinical trials. Our goal is to provide industry leading MRD sensitivity that can provide actionable information to physicians and pharmaceutical companies to enhance a personalized approach to cancer treatment.”

Jake Chabon, PhD
CEO and Co-Founder of Foresight Diagnostics

Jake Chabon Headshot

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