Foresight Diagnostics is a cancer diagnostics company developing a novel liquid biopsy test for the measurement of minimal residual disease (MRD) for aid in patient management that is funded by leading diagnostics VC firms in Silicon Valley. Foresight’s cell-free DNA testing platform was developed in the labs of two prominent professors at Stanford University and is backed by several major Cell and Nature publications. The company has garnered significant partnering interest from multiple pharmaceutical companies in oncology and is poised for rapid growth. Foresight Diagnostics is headquartered in Aurora, Colorado.
As a new member of our cross-functional team, you will be responsible for assisting in the testing activities of a new technology that allows for quicker cancer diagnostics. You have a degree in a wet science and a couple of years of research experience in NGS, PCR and/or bio sample management. BUT, what sets you apart is your intense curiosity and drive for a solution. You are meticulously organized and enjoy brainstorming with your team to find improvements in assay performance. This is a unique opportunity to work in a profitable production lab researching diagnostics that will greatly impact cancer treatment. If you want to be a part of the future of cancer diagnostics, let’s chat!
Responsibilities
Performing analytical testing activities, including specimen accessioning, testing, quality control, and validation studies according to laboratory operating procedures.
Maintaining reagents, consumables, stock solutions and supply inventory, including preparation and aliquoting of reagents
Collaborating with R&D to design and analyze data for assessing assay performance
Maintaining accurate documentation and taking corrective actions when test deviates from established performance specifications
Following procedures to ensure safety, security, quality and accuracy of results
Jumping in to help wherever you can to make a difference
Requirements
BS/BA in Molecular Biology or another Wet Science
At least 2 years of laboratory research in NGS, PCR and/or bio sample management – CLIA lab experience is a plus.
Deep understanding of scientific principles, testing procedures, and molecular biology techniques
Strong aseptic laboratory skills with the ability to perform precise, complex lab procedures
Inquisitive and analytical mind driven by data yet flexible and open to new ideas
Exceptional communication skills; written and verbal, with an innate ability to listen actively and query insightfully
Proficient with Excel, Word and PowerPoint
Dedicated to making a difference in a fast-paced startup environment.
Compensation
We offer highly competitive salary and benefits combined with a generous equity package. You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Salary $50,000 - $65,000 depending on experience.
The Head of Laboratory Operations at Foresight Diagnostics (specific title to be determined based on experience) will lead and participate in the global operations of the business to ensure that the CLIA laboratory and client experience is exemplary. Additionally, this role has the opportunity to be customer facing with pharmaceutical and biotechnology partners. The successful candidate will be a hands-on leader who will manage the CLIA certified laboratory and team.
Responsibilities
Support the business in delivering world-class cancer diagnostics data to customers on time and on budget.
Lead the design, execution, and report generation for analytical validation studies.
Manage and scale day to day operations in the lab to ensure project timelines and quality objectives are met. Responsibilities include logistics, supply chain and chain of custody control, inventory and reagent management.
Selection, implementation and ongoing maintenance of laboratory software systems, including eQMS, LIMS, inventory management, e-lab notebooks.
Develop and deploy the strategy for ongoing platform automation and scaling of molecular biology workflows to increase throughput and decrease turnaround time.
Develop, expand & lead the operations team.
Requirements
BA/BS in Molecular Biology, Biochemistry, or a related life science field.
7+ years of experience in the life sciences or biotechnology industry.
Experience in the operations and launch of novel complex diagnostics into growing markets; managing to timelines.
Past experience in working with and managing multiple outside vendors and Pharmaceutical Partners, including internationally.
Demonstrated ability to recruit quality talent and lead high performing teams.
Proven experience in scaling operations from early stage to higher demands due to significant growth.
Experience interfacing with regulatory bodies.
Understanding of companion diagnostics and LDTs.
Solid knowledge of cancer diagnostic product development.
Ability to operate cross functionally at multiple levels of the organization; effective at managing relationships with direct reports, peers and the Board and CEO.
Preferred Experience
Advanced degree (Ph.D, MD, or MS) in Molecular Biology, Biochemistry, or a related life science field.
Prior experience in working in a startup environment.
Experience with Illumina’s NGS instrumentation equipment (NovaSeq).
A technical background is highly preferred for this role, with an understanding of molecular biology and genomics.
Understanding of database implementation and management.
Compensation
We offer highly competitive salary and benefits combined with a generous equity package. You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Salary $100,000 - $150,000 depending on experience.
The Manager of Quality Management Systems, is a strategic position reporting to the CEO, responsible for the development, implementation, and maintenance of the Quality Program including Quality Assurance (QA), the Quality Management System (QMS), and supplier quality to ensure compliance with relevant ISO standards and FDA regulations such as ISO 13485:2016 and ISO 14971:2012.
Functions include management, oversight and monitoring of CAPA, Complaints, Management Review, Document and Records Control, Training, and Internal Audit. Assure that relevant procedures are managed and continuously reviewed and improved for compliance and operating efficiencies.
Responsibilities
Implement and maintain the necessary programs to support the Corporate Quality Policy, the Quality System, and Continuous Improvement initiatives as they relate to the QMS.
Build strong quality systems for determining the appropriate infrastructure and resources required for department to achieve business objectives.
Assume responsibilities for the Quality Management System (software design life cycle, assay design control, production support, supplier approval process including audits, complaints, document control, training program, etc.)
Develop quality performance indicators.
Support hosting internal and external audits, review audit reports, and follow up on required actions.
Organize, oversee and lead management of CAPA, Complaints, Management Review, Document and Records Control, Training and Internal Audit, approving plans and expenditures necessary to achieve objectives.
Perform other duties as assigned by supervisor.
Requirements
Bachelor's degree in a scientific field or applicable experience.
Minimum of 10 years experience effectively utilizing/implementing a QMS that compiles to CFR820 and ISO13485.
Minimum of 5 years managing and mentoring Quality Engineers and/or Quality Assurance Specialists.
Experience in managing/participating in external audits by regulatory bodies directed against the QMS.
Attention to detail with an ability to technically create and review documentation.
Ability to interact with multiple disciplines, and communicate clearly and effectively verbally and in writing.
Ability to work independently, and utilize good problem-solving skills.
Ability to multitask and work within a fast-paced dynamic team environment.
Preferred Experience
Prior experience in working in a startup environment.
Prior experience in the molecular diagnostics industry.
Background in molecular biology and/or cancer biology.
Experience with Illumina's NGS instrumentation equipment.
A technical background is highly preferred for this role, with an understanding of molecular biology and genomics.
Compensation
We offer highly competitive salary and benefits combined with a generous equity package. You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
This hire may be transitioned to higher positions within Quality as experience and skills prove appropriate.
Salary $90,000 - $150,000 depending on experience.
As a core member of our team, you will be acting as the technical lead; driving R&D efforts for new product introductions and regulatory submissions of cutting-edge cancer diagnostic NGS assays. You are a scientist with a track record of professional success evidenced by your strategic career trajectory. Your academic research and recent industry experience have provided you a deep technical understanding of NGS assays and data analysis. You thrive in a collaborative team environment. This is a unique opportunity to work in a profitable production lab researching diagnostics that will greatly impact cancer treatment. If you want to be a part of the future of cancer diagnostics, let’s chat!
Responsibilities
Developing and validating cutting-edge cancer diagnostic NGS assays
Driving the development efforts to optimize assay performance and improve laboratory processes
Performing complex analysis of large genomic data sets in collaboration with the bioinformatics team
Maintaining documentation in compliance with Good Laboratory Practices and Quality Systems Requirements
Collaborating toward the best outcomes, presenting updates, analyses and conclusions
Following procedures to ensure safety, security, quality, and accuracy of results
Mentoring junior team members so we all continue to grow!
Requirements
Ph.D. in Molecular Biology or Biochemistry
Postdoc academic research and at least 2 years of industry experience or 4 years of industry in lieu of postdoc research
Deep technical understanding of NGS assay development and NGS data analysis
Demonstrated experience with NGS library preparation, hybrid capture-based target enrichment and Illumina sequencing workflows
Passion for growing junior scientists through coaching and leading by example
Ability to design and interpret results aimed at improving assay performance
Proficiency with Python, R, Bash scripting or similar languages will get our attention!
Experience with standard NGS bioinformatic tools and external genomic datasets
Confident communicator with an innate ability to listen actively, query insightfully and deliver information respectfully
Humility, competency and curiosity - you know your stuff but enjoy brainstorming with others for the best outcome
Dedicated to making a difference in a fast-paced startup environment.
Compensation
We offer highly competitive salary and benefits combined with a generous equity package. You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
Salary $90,000 - $125,000 depending on experience.
You are a key component of our fast-paced company! We have lots of moving parts, and we’re looking for your infectious energy and positive demeanor wrapped in technically savvy organizational superpowers. You thrive in a mildly chaotic environment where your ability to unpack problematic details and craft efficiencies is celebrated! You’ll be doing a little bit of everything – HR, office administration and executive support – juggling all the priorities while remaining calm. You have been an office administrator and are excited to move forward with a career in human resources, so this sounds like your dream come true. If you want to be a part of the future of cancer diagnostics, let’s chat!
Responsibilities
Managing and organizing the day-to-day operations of a fast-paced growing office – human resources, office administration and executive support
Supporting the design, furnishing and buildout of a new office space that the company will be moving into in Q2 2022 and ongoing general facility oversite
Performing all HR Generalist functions such as: Managing employee onboarding, assisting with and backup for payroll; basic compliance & training, and collecting employee data – of course with the utmost confidentiality
Leading the creation of benefits programs that include healthcare, 401k, professional development and perks like a contest for the best Halloween costume – you get the idea….
Making sure the team has everything they need to get their jobs done – anticipating their needs, listening for potential obstacles, and clearing them in advance – you’re the glue that holds us all together!
Providing agile support for the CEO and CFO – managing calendars, organizing documents, and planning meetings and events
Leveraging technology to automate, inform and increase productivity
Helping fortify our values-based culture as an inspirational leader and positive mentor – oh and planning fun events so that we all get a chance to enjoy each other out of the office
Jumping in to help wherever you can to maintain an effective organization where everyone can focus on their strengths!
Requirements
BS/BA in a business discipline or equivalent work experience
At least 5 years of professional experience as an office manager with HR and administration responsibilities – bonus points for your work in a startup or biotech
Excellent communicator who understands the importance of being a good listener
Brilliantly organized, resourceful, and self-directed – you are a system thinker and a fan of automation
Superior command of Outlook, Excel, PowerPoint as well as office productivity apps like Slack and G-Suite
A sharp mind capable of handling multiple, sometimes competing, priorities without breaking a sweat
Friendly, outgoing, engaging personality - you truly enjoy helping people
Compensation
We offer highly competitive salary and benefits combined with a generous equity package. You will be working on interesting problems with extremely high impact. We promote the professional development of our employees and will encourage upward mobility within the company for high performing employees. Foresight Diagnostics is an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
